Ongoing Research

Ongoing Research

BRAIN-ICU-2

BRAIN-ICU-2

This is an exciting and upcoming study designed to understand the link between delirium and dementia after critical illness.

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CADUCEUS

CADUCEUS

An ancillary study of inflammation levels in the blood of critically ill patients.

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CO-PILOT

CO-PILOT

An ancillary study to determine how oxygen levels during mechanical ventilation affect long-term cognition.

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COPE

COPE

A study of the effects of prehabilitation on physical and cognitive recovery in surgery patients.

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COVID-D

COVID-D

An International study of the risk factors and epidemiology of delirium and coma in COVID-19 patients while admitted to the ICU

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DeCat

DeCat

An ongoing investigational cohort study of delirium and catatonia in critically ill patients.

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INSIGHT-ICU

INSIGHT-ICU

An ongoing comprehensive long-term cognitive impairment study after traumatic injury and critical illness.

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ISOLATE-ICU

ISOLATE-ICU

A national study of the effect of COVID-related isolation policies on patients, families, and healthcare providers in the ICU

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MENDS-3

MENDS-3

A multicenter study of the role of a new drug for ICU delirium in COVID-19 patients

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MENDS2

MENDS2

An ongoing randomized controlled trial to determine the best sedative medication to reduce delirium and improve survival and long-term brain function in ventilated septic patients.

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MIND-USA

MIND-USA

After 40 years of using antipsychotics to treat delirium in millions of ICU patients, the MIND-USA finally provides a placebo-controlled treatment trial to answer the question: Do these medications reduce delirium and improve other clinical outcomes better than sugar water in ICU patients?

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MOSAIC

MOSAIC

An ongoing observational study of the association between activity and physical and cognitive function in ICU survivors.

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ORCHID-BUD

ORCHID-BUD

A national study (sponsored by NIH-NIA) to understand long-term cognitive function, PTSD, and depression in COVID-19 survivors

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SCOPE

SCOPE

An ongoing randomized controlled trial to evaluate the effect of specialist palliative care on quality of life for patients undergoing major abdominal operations for cancer.

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mini-MENDS

mini-MENDS

A randomized controlled trial to determine the best sedative medication to reduce delirium and improve functional and behavioral recovery in pediatric patients.

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