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Cognitive, Psychological, and
Quality of Life Outcomes Post-ICU Stay

Jackson JC, Obremskey W, Bauer R et al. Long-term cognitive, emotional, and functional outcomes in trauma intensive care unit survivors without intracranial hemorrhage. J Trauma. 2007;62:80-88. http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=Citation&list_uids=17215737.

G. L. Bryson and A. Wyand. Evidence-based clinical update: General anesthesia and the risk of delirium and postoperative cognitive dysfunction: [Mise a jour clinique fondee sur des donnees probantes : l'anesthesie generale et le risque de delire et de dysfonctionnement cognitif postoperatoire]. Can.J Anaesth. 53 (7):669-677, 2006.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16803914&query_hl=27&itool=pubmed_docsum.

H. K. Fong, L. P. Sands, and J. M. Leung. The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review. Anesth.Analg. 102 (4):1255-1266, 2006.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=Search&DB=pubmed.

J. E. Nelson, N. Tandon, A. F. Mercado, S. L. Camhi, E. W. Ely, and R. S. Morrison. Brain dysfunction: another burden for the chronically critically ill. Arch.Intern.Med. 166 (18):1993-1999, 2006.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17030833&query_hl=30&itool=pubmed_docsum

R. O. Hopkins, L. K. Weaver, D. Collingridge, R. B. Parkinson, K. J. Chan, and J. F. Orme, Jr. Two-Year Cognitive, Emotional, and Quality-of-Life Outcomes in Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med 171 (4):340-347, 2005.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15542793

J. C. Jackson, S. M. Gordon, R. P. Hart, R. O. Hopkins, and E. W. Ely. The association between delirium and cognitive decline: a review of the empirical literature. Neuropsychol Rev 14 (2):87-98, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15264710

J. C. Jackson, S. M. Gordon, E. W. Ely, C. Burger, and R. O. Hopkins. Research issues in the evaluation of cognitive impairment in intensive care unit survivors. Intensive Care Med 2004;2009-2016.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15372146

S. M. Gordon, J. C. Jackson, E. W. Ely, C. Burger, and R. O. Hopkins. Clinical identification of cognitive impairment in ICU survivors: insights for intensivists. Intensive Care Med 30:1997-2008, 2004.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15549252

Hopkins, R.O., Weaver, L.K., Pope, D., Orme, J.F., Bigler, E.D., Larson-Lohr, V. Neuropsychological sequelae and impaired health status in survivors of severe acute respiratory distress syndrome. Am J Respir Crit Care Med 1999; 160:50-56.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10390379&dopt=Abstract

Jackson, J.C., Hart, R.P., Gordon, S.M., Shintani, A., Truman, B., May, L. et al. Six-month neuropsychological outcome of medical intensive care unit patients. Crit Care Med 2003; 31:1226-1234.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12682497&dopt=Abstract

Rothenhausler, H.B., Ehrentraut, S., Stoll, C., Schelling, G., Kapfhammer, H.P.. The relationship between cognitive performance and employment and health status in long-term survivors of the acute respiratory distress syndrome: results of an exploratory study. General Hospital Psychiatry 2001; 23:90-96.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11313077&dopt=Abstract

Schelling, G., Stoll, C., Haller, M., Briegel, J., Manert, W., Hummel, T. et al. Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome. Crit Care Med 1998; 26:651-659.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9559601&dopt=Abstract

Scragg, P., Jones, A., Fauvel, N.. Psychological problems following ICU Treatment. Anesthesia 2001; 56: 9-14.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11167429&dopt=Abstract

Vanderbilt University Medical Center
Veterans Affairs TN Valley Geriatric Research Education and Clinical Center (GRECC)